Herzog B, Steigert M, Hadziselimovic F
Department of Pediatric Andrology, University Children's Hospital, Basel, Switzerland.
J Urol. 1992 Aug;148(2 Pt 2):622-3. doi: 10.1016/s0022-5347(17)36671-5.
In a clinical study 96 prepubertal boys with 100 testes located in the superficial inguinal pouch underwent routine orchiopexy. Of 65 patients 45 (69%) who had received hormonal treatment before the surgical procedure had a closed processus vaginalis compared with only 11 of 35 (31%) who had not (p less than 0.0002). A normal epididymis was also present significantly more often in those patients receiving hormonal treatment than in those who did not (p less than 0.039). While those testes located in the superficial inguinal pouch had significantly better histology and a greater number of germ cells than those located in a high inguinal or abdominal position (p less than 0.01), the number of germ cells per tubule was nonetheless lower than that seen in the normal controls (p less than 0.01). In conclusion, a testis located at the superficial inguinal pouch behaves as a true cryptorchid testis. Furthermore, hormonal treatment before surgery has a significant effect on epididymal development and closure of the processus vaginalis.
在一项临床研究中，96名青春期前男孩的100个睾丸位于腹股沟浅袋，接受了常规睾丸固定术。在65名患者中，45名（69%）在手术前接受过激素治疗，其鞘突已闭合，而未接受激素治疗的35名患者中只有11名（31%）鞘突闭合（p<0.0002）。接受激素治疗的患者中，正常附睾的出现频率也显著高于未接受激素治疗的患者（p<0.039）。虽然位于腹股沟浅袋的睾丸组织学明显优于位于高位腹股沟或腹腔位置的睾丸，且生殖细胞数量更多（p<0.01），但每个小管的生殖细胞数量仍低于正常对照组（p<0.01）。总之，位于腹股沟浅袋的睾丸表现为真正的隐睾。此外，手术前的激素治疗对附睾发育和鞘突闭合有显著影响。
