BROWN A W
Bull World Health Organ. 1958;18(3):309-21.
The author reviews the growth of the insecticide-resistance problem throughout the world during the period between July 1956 and November 1957, and the developments in research on the subject during the same period.Three new resistant species have been discovered-Anopheles subpictus, Chrysomyia putoria and Rhipicephalus sanguineus-and eight new types of resistance in already resistant species have been observed. Moreover, the geographical area covered by certain resistant insect populations has considerably increased.THE RESEARCH ACCOMPLISHMENTS DURING THE PERIOD UNDER REVIEW INCLUDE: systems of detecting resistance in the field by standard test methods; confirmation of two distinct types of resistance to chlorinated-hydrocarbon insecticides in mosquitos and bed-bugs as well as in houseflies; evidence that DDT-resistance in the housefly, Anopheles sundaicus and Aëdes aegypti is due mainly to a single genetic factor associated with the ability to dehydrochlorinate DDT, and that dieldrin-resistance of Anopheles gambiae also derives from a single factor present even in untouched populations; a fuller understanding of the physiological mechanism of BHC-resistance in the housefly; and demonstration that selection pressure from organo-phosphorus compounds induces resistance to themselves and to chlorinated-hydrocarbon insecticides.
作者回顾了1956年7月至1957年11月期间全球范围内抗杀虫剂问题的发展情况，以及同期该主题的研究进展。已发现三种新的抗性物种——伪嗜人按蚊、恶臭金蝇和血红扇头蜱，并且在已具抗性的物种中观察到了八种新的抗性类型。此外，某些抗性昆虫种群覆盖的地理区域已大幅增加。在所述期间的研究成果包括：通过标准测试方法在野外检测抗性的系统；证实了蚊子、臭虫以及家蝇对氯代烃类杀虫剂存在两种不同类型的抗性；有证据表明，家蝇、辛氏按蚊和埃及伊蚊对滴滴涕的抗性主要归因于与滴滴涕脱氯化氢能力相关的单一遗传因素，而冈比亚按蚊对狄氏剂的抗性也源于即使在未接触过该药剂的种群中也存在的单一因素；对家蝇中六六六抗性生理机制有了更全面的了解；以及证明有机磷化合物产生的选择压力会导致昆虫对其自身以及氯代烃类杀虫剂产生抗性。
