三碘甲状腺原氨酸对发育中鸡胚肝脏中环磷酸腺苷（cAMP）依赖性和非cAMP依赖性蛋白激酶活性的影响。

Effect of triiodothyronine on cAMP-dependent and cAMP-independent protein kinase activities in developing chick embryo liver.

Gavrilova N J, Setchenska M S, Dimitrova M

Central Laboratory of Biophysics, Bulgarian Academy of Sciences, Sofia.

Comp Biochem Physiol Comp Physiol. 1992 Jun;102(2):245-8. doi: 10.1016/0300-9629(92)90128-d.

Abstract

Changes in liver cytosol cAMP-dependent kinase and cAMP-independent growth-related quercetin-inhibited casein kinase activities during chick embryo development were studied. 2. Both kinase activities were found to increase continuously during the experimental period. 3. Upon treatment of embryos with triiodothyronine, an activation of cAMP-dependent kinase A and cAMP-independent casein kinase was observed which was most pronounced on days 12 and 14.

摘要

研究了鸡胚发育过程中肝脏胞质中依赖环磷酸腺苷（cAMP）的激酶以及与生长相关的非依赖cAMP的槲皮素抑制酪蛋白激酶活性的变化。2. 在实验期间发现这两种激酶活性均持续增加。3. 用三碘甲状腺原氨酸处理胚胎后，观察到依赖cAMP的蛋白激酶A和非依赖cAMP的酪蛋白激酶被激活，在第12天和第14天最为明显。