Adaptation effect of sucrose on the salt taste response.

1. Intracellular recordings from mouse taste receptor cells were made to study cellular adaptation properties. 2. The sugar and salt receptor mechanisms of mammalian taste cells were investigated with cross-adaptation experiments. 3. The responding of taste cells to sucrose as well as to NaCl does not contradict the independency of their binding mechanisms. 4. With a mixture of sucrose and NaCl, different adsorption mechanisms are observed. 5. From these observations, it was concluded that adaptation occurs in the taste receptor cell.