喹乙吲哚的抗组胺活性：一种2-取代的吡嗪并吡啶吲哚衍生物。
Antihistaminic activity of quinethindole: a 2-substituted pyrazinopyridoindole derivative.
作者信息
Patnaik G K, Saxena A K, Saxena M, Srimal R C
机构信息
Central Drug Research Institute, Lucknow, India.
出版信息
Indian J Exp Biol. 1992 Feb;30(2):144-6.
PMID:1355754
Abstract
Quinethindole, a 2-substituted pyrazinopyridoindole, showed specific antihistaminic (H1) activity in various in vivo and in vitro test models. It also inhibited antigen-induced contraction of ileum of sensitized guinea pig. The antihistaminic activity was of competitive nature.
摘要
喹内西朵，一种2-取代的吡嗪并吡啶吲哚，在各种体内和体外测试模型中显示出特异性抗组胺（H1）活性。它还抑制致敏豚鼠回肠的抗原诱导收缩。抗组胺活性具有竞争性。
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