Anichkov N M, Serezhin B S, Lomakina I I, Smirnov O A
Arkh Patol. 1992;54(2):33-9.
55 endometrial carcinomas containing apud cells are studied. Correlation between the endocrine-metabolic disturbances and mitotic index, on the one hand, and number of apud cells and their product on the other, is revealed. If the percentage of apud cells is above 20 of all parenchymal cells, low mitotic index in the tumour, marked production of serotonin, calcitonin and other hormones and high incidence of endocrine disturbances together with a relatively favourable prognosis are observed. Low number of apud cells associated with high mitotic index and high incidence of unfavourable outcomes while the hormone production and endocrine disturbances were rare or absent.
对55例含有APUD细胞的子宫内膜癌进行了研究。揭示了内分泌代谢紊乱与有丝分裂指数之间的相关性,以及APUD细胞数量与其产物之间的相关性。如果APUD细胞在所有实质细胞中的百分比高于20%,则可观察到肿瘤有丝分裂指数低、血清素、降钙素和其他激素的大量产生、内分泌紊乱的高发生率以及相对良好的预后。APUD细胞数量少与有丝分裂指数高和不良结局的高发生率相关,而激素产生和内分泌紊乱则很少见或不存在。