γ干扰素改变小鼠念珠菌病中CD4 +亚群的表达。
Gamma interferon modifies CD4+ subset expression in murine candidiasis.
作者信息
Romani L, Cenci E, Mencacci A, Spaccapelo R, Grohmann U, Puccetti P, Bistoni F
机构信息
Department of Experimental Medicine and Biochemical Sciences, University of Perugia, Italy.
出版信息
Infect Immun. 1992 Nov;60(11):4950-2. doi: 10.1128/iai.60.11.4950-4952.1992.
Abstract
A single injection of monoclonal antibody to gamma interferon administered in conjunction with a live Candida albicans yeast cell vaccine resulted in the detection of nonprotective Th2 rather than protective Th1 responses and altered the early expression of interleukin 4 and gamma interferon mRNA in CD4+ cells.
摘要
单次注射γ干扰素单克隆抗体并联合白色念珠菌活酵母细胞疫苗，导致检测到非保护性的Th2反应而非保护性的Th1反应，并改变了CD4⁺细胞中白细胞介素4和γ干扰素mRNA的早期表达。
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