Karvonen J, Poikolainen K, Reunala T, Juvakoski T
Department of Dermatology, University Hospital of Oulu, Finland.
Acta Derm Venereol. 1992;72(3):208-10.
Risk factors for infectious eczematoid dermatitis (IED) were analyzed in a study of males aged 19-50 years. The subjects were 43 IED patients and 226 controls with other skin diseases from the dermatological outpatient clinics of three University Hospitals in Finland. The patients' lifestyles were assessed by a self-administered questionnaire pertaining to two specified periods: the period 12 months before the onset of the skin disease and the period 12 months before the examination date. Recalled mean alcohol intake before the onset of the skin disease was 39.2 g/day for the IED patients and 17.1 g/day for the controls (p = 0.04). The average number of cigarettes smoked daily was 17.7 for the IED patients and 10.4 for the control patients (p = 0.001). The IED patients significantly reduced their alcohol intake after the onset of the skin disease. In logistic regression analysis, IED associated with alcohol intake and smoking but not with coffee consumption, life events, age, marital status, or social group. The odds ratio for IED at an alcohol intake of 50 g/day as against no intake, was 1.7 (95% confidence interval 1.03-2.7), and the odds ratio at a tobacco consumption rate of 20 cigarettes/day as against no use of tobacco, was 2.1 (1.2-3.7). We conclude that alcohol intake and smoking appear to be risk factors for infectious eczematoid dermatitis among males.
在一项针对19至50岁男性的研究中，分析了感染性湿疹样皮炎（IED）的危险因素。研究对象为43例IED患者和226例来自芬兰三所大学医院皮肤科门诊的患有其他皮肤病的对照者。通过一份针对两个特定时期的自填问卷对患者的生活方式进行评估：皮肤病发作前12个月期间以及检查日期前12个月期间。IED患者在皮肤病发作前回忆的平均酒精摄入量为每日39.2克，对照者为每日17.1克（p = 0.04）。IED患者每日平均吸烟量为17.7支，对照患者为10.4支（p = 0.001）。IED患者在皮肤病发作后显著减少了酒精摄入量。在逻辑回归分析中，IED与酒精摄入和吸烟有关，但与咖啡消费、生活事件、年龄、婚姻状况或社会群体无关。酒精摄入量为每日50克相对于不饮酒时，IED的优势比为1.7（95%置信区间1.03 - 2.7），烟草消费率为每日20支相对于不吸烟时，IED的优势比为2.1（1.2 - 3.7）。我们得出结论，酒精摄入和吸烟似乎是男性感染性湿疹样皮炎的危险因素。
