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感染母亲所生未感染儿童对曼氏血吸虫抗原的致敏作用。

Sensitization to Schistosoma mansoni antigen in uninfected children born to infected mothers.

作者信息

Camus D, Carlier Y, Bina J C, Borojevic R, Prata A, Capron A

出版信息

J Infect Dis. 1976 Oct;134(4):405-8. doi: 10.1093/infdis/134.4.405.

DOI:10.1093/infdis/134.4.405
PMID:135812
Abstract

Sensitization to Schistosoma mansoni antigen in uninfected children born to infected or uninfected mothers was studied by intradermal reaction. Immediate skin reaction, Arthus phenomenon, and delayed skin responses were noted. The skin response at 24 hr was positive in 48.1% of the uninfected children born to infected mothers, and in only 7.5% of uninfected (control) children born to uninfected mothers. Areas of skin reactions were also larger in the group born to infected mothers. Both of these differences were statistically significant. There were no significant variations according to age or sex. Only one immediate skin reaction was noted in each group, and Arthus phenomenon was never observed.

摘要

通过皮内反应研究了感染或未感染母亲所生未感染儿童对曼氏血吸虫抗原的致敏情况。记录了即刻皮肤反应、阿瑟斯现象和迟发性皮肤反应。感染母亲所生未感染儿童中,48.1%在24小时时皮肤反应呈阳性,而未感染母亲所生未感染(对照)儿童中只有7.5%呈阳性。感染母亲所生孩子组的皮肤反应面积也更大。这两个差异均具有统计学意义。根据年龄或性别没有显著差异。每组仅观察到1例即刻皮肤反应,从未观察到阿瑟斯现象。

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