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津巴布韦城市儿童急性中毒模式:十年经验

A pattern of acute poisoning in children in urban Zimbabwe: ten years experience.

作者信息

Kasilo O M, Nhachi C F

机构信息

Department of Pharmacy, University of Zimbabwe Medical School, Avondale, Harare.

出版信息

Hum Exp Toxicol. 1992 Sep;11(5):335-40. doi: 10.1177/096032719201100506.

Abstract
  1. A retrospective analysis was performed to evaluate the epidemiology of poisoning in children based on admissions to six of Zimbabwe's main urban hospitals over a 10-year period from 1980 to 1989 inclusive. 2. A total of 2873 cases were children aged between 0-15 years. This constituted 47.8% of poisoning cases from all age groups (6018) recorded during the study period. 3. All of the children (0-15 years) had signs and symptoms of poisoning on admission and, depending on their severity, were admitted to a ward or to an intensive care unit. A total of 4.9% (141) died. Most of those who died were suicide cases among the 11-15 year age group and accidental poisonings among the 0-15 year old group. 4. The under 0-5 age group constituted the majority of cases (75.4%) in the 0-15 age group, and most were between 1 and 3 years old. The 6-10 and 11-15 age groups formed 12.6% and 12% of the cases, respectively. The sex distribution showed that 53.1% were male. 5. Most incidences were accidental (93.2%). Suicides and parasuicides accounted for 1.9% and there were only two homicides. 6. The commonest toxic agents were: household products (27.2%), traditional medicines (23.%), venoms from snake bites and insect stings (16%) and therapeutic agents (12.4%). Of the therapeutic agents the most frequently implicated were antipsychotics 18.9%, analgesics 16.8%, anti-infectives 11.7%, anticonvulsants (8.2%) and benzodiazepines (7.7%).(ABSTRACT TRUNCATED AT 250 WORDS)
摘要
  1. 进行了一项回顾性分析,以评估1980年至1989年(含)这10年间,津巴布韦6家主要城市医院收治儿童中毒病例的流行病学情况。2. 共有2873例病例为0至15岁的儿童。这占研究期间记录的所有年龄组中毒病例(6018例)的47.8%。3. 所有0至15岁的儿童入院时均有中毒的体征和症状,并根据严重程度被收治到病房或重症监护病房。共有4.9%(141例)死亡。死亡者大多是11至15岁年龄组的自杀病例以及0至15岁组的意外中毒病例。4. 0至5岁年龄组占0至15岁年龄组病例的大多数(75.4%),且大多在1至3岁之间。6至10岁和11至15岁年龄组分别占病例的12.6%和12%。性别分布显示,男性占53.1%。5. 大多数中毒事件为意外(93.2%)。自杀和准自杀占1.9%,仅有两起他杀事件。6. 最常见的毒物为:家用产品(27.2%)、传统药物(23%)、蛇咬和虫蜇毒液(16%)以及治疗药物(12.4%)。在治疗药物中,最常涉及的是抗精神病药(18.9%)、镇痛药(16.8%)、抗感染药(11.7%)、抗惊厥药(8.2%)和苯二氮䓬类药物(7.7%)。(摘要截选至250词)

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