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二氧化碳激光锥切术作为宫颈原位癌患者的子宫保留手术。

Conization with a carbon dioxide laser as a uterine-preservation operation for patients with preinvasive cervical carcinoma.

作者信息

Chen R J, Hsieh C Y, lee T Y, Lee F E, Kao M C

机构信息

Department of Obstetrics and Gynecology, College of Medicine, National Taiwan University, Taipei, R.O.C.

出版信息

J Formos Med Assoc. 1992 May;91(5):521-5.

PMID:1358331
Abstract

Preinvasive cervical carcinoma (PCC) is a disease entity of the uterine cervix resulting from carcinoma in situ and various degrees of dysplasia. These cases are conventionally treated by a total abdominal hysterectomy. Effective management that can preserve the uterus is more desirable than hysterectomy. In this report, we present the results and complications of laser conization as a uterine-preservation treatment. At our dysplasia clinic, cases of reproductive age diagnosed with PCC can voluntarily undergo laser conization. From June 1985 to May 1988, there were 26 cases who received this treatment. After treatment, they were regularly followed up for more than three years. Before and after surgery, these cases were evaluated by a Pap smear for cytology, colposcopy, a cervical punch biopsy and endocervical curettage for histopathology. Eighteen cases with a satisfactory colposcopy were treated by laser vaporizing conization. Eight cases with an unsatisfactory colposcopy were treated by laser excisional conization. Their mean age was 35.8 (SD 7.7) years, and parity was 1.5 (SD 0.9). The instrument used was a Sharplan CO2 laser model 720. The power density was around 1,000 W/cm2 for vaporization, and 1,500 W/cm2 for excisional conization. During the operations, there was little bleeding. No case required a blood transfusion. The vaginal discharge decreased within four days after treatment. The cervical epithelium on the operated wound began growing after the second week, and the cervix healed well in four to six weeks. After healing, the squamocolumnar junction in each case was visible on colposcopy. No case suffered from cervical stenosis.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

宫颈原位癌(PCC)是子宫颈的一种疾病实体,由原位癌和不同程度的发育异常引起。这些病例传统上采用全腹子宫切除术治疗。能保留子宫的有效治疗方法比子宫切除术更可取。在本报告中,我们介绍了激光锥切术作为一种保留子宫治疗方法的结果和并发症。在我们的发育异常诊所,诊断为PCC的育龄病例可自愿接受激光锥切术。1985年6月至1988年5月,有26例接受了这种治疗。治疗后,他们接受了超过三年的定期随访。手术前后,通过巴氏涂片进行细胞学评估、阴道镜检查、宫颈穿刺活检和宫颈管刮除术进行组织病理学评估。18例阴道镜检查结果满意的病例采用激光汽化锥切术治疗。8例阴道镜检查结果不满意的病例采用激光切除锥切术治疗。他们的平均年龄为35.8(标准差7.7)岁,产次为1.5(标准差0.9)。使用的仪器是Sharplan CO2激光720型。汽化的功率密度约为1000 W/cm2,切除锥切术的功率密度为1500 W/cm2。手术过程中出血很少。无一例需要输血。治疗后四天内阴道分泌物减少。手术伤口处的宫颈上皮在第二周后开始生长,宫颈在四至六周内愈合良好。愈合后,通过阴道镜检查可看到每个病例的鳞柱交界。无一例发生宫颈狭窄。(摘要截短至250字)

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