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核心技术专利：CN118964589B侵权必究

核心技术专利：CN118964589B侵权必究

Gibson I C, Logan S D

Department of Physiology, Medical School, Edgbaston, Birmingham, U.K.

Comp Biochem Physiol C Comp Pharmacol Toxicol. 1992 Jun;102(2):297-303. doi: 10.1016/0742-8413(92)90115-n.

Voltage-clamp recordings have been made from identified neurones in the suboesophageal ganglia of Helix aspersa. 2. Calcium currents were isolated pharmacologically and studied under two-electrode voltage-clamp. 3. PdBu but not PMA caused a transient enhancement followed by an irreversible inhibition of the calcium current. 4. It is concluded that activation of protein kinase C within these neurones may show selectivity with respect to the exogenous activator used.

已对花园蜗牛食管下神经节中已鉴定的神经元进行了电压钳记录。2. 通过药理学方法分离出钙电流，并在双电极电压钳下进行研究。3. 佛波酯（PdBu）而非佛波醇-12-肉豆蔻酸酯-13-乙酸酯（PMA）引起钙电流的短暂增强，随后是不可逆抑制。4. 得出的结论是，这些神经元内蛋白激酶C的激活可能对外源性激活剂具有选择性。

Gibson I C, Logan S D

Department of Physiology, Medical School, Edgbaston, Birmingham, U.K.

Comp Biochem Physiol C Comp Pharmacol Toxicol. 1992 Jun;102(2):297-303. doi: 10.1016/0742-8413(92)90115-n.

Voltage-clamp recordings have been made from identified neurones in the suboesophageal ganglia of Helix aspersa. 2. Calcium currents were isolated pharmacologically and studied under two-electrode voltage-clamp. 3. PdBu but not PMA caused a transient enhancement followed by an irreversible inhibition of the calcium current. 4. It is concluded that activation of protein kinase C within these neurones may show selectivity with respect to the exogenous activator used.

已对花园蜗牛食管下神经节中已鉴定的神经元进行了电压钳记录。2. 通过药理学方法分离出钙电流，并在双电极电压钳下进行研究。3. 佛波酯（PdBu）而非佛波醇-12-肉豆蔻酸酯-13-乙酸酯（PMA）引起钙电流的短暂增强，随后是不可逆抑制。4. 得出的结论是，这些神经元内蛋白激酶C的激活可能对外源性激活剂具有选择性。