AMANO T, GOEBEL W F, SMIDTH E M
J Exp Med. 1958 Nov 1;108(5):731-52. doi: 10.1084/jem.108.5.731.
By immunological means it has been shown that colicine K is associated with the O antigen of the colicinogenic bacillus E. coli K(235) L(+)OC(+). The colicine K-O antigen complex elicits the formation of at least two types of antibodies, one a precipitin, the other a colicine-neutralizing antibody. The first precipitates colicine K without neutralizing it, the second neutralizes the colicine without precipitating it. Unlike the purified colicine K complex, the colicine protein component of the O antigen is precipitable by the neutralizing antibody. There is no demonstrable serological relationship between colicine K and phage T(6). These two agents must be considered to be separate and distinct entities.
通过免疫学方法已表明,大肠杆菌素K与产大肠杆菌素的大肠杆菌K(235)L(+)OC(+)的O抗原相关。大肠杆菌素K - O抗原复合物至少能引发两种类型抗体的形成,一种是沉淀素,另一种是大肠杆菌素中和抗体。第一种能沉淀大肠杆菌素K但不使其中和,第二种能中和大肠杆菌素但不使其沉淀。与纯化的大肠杆菌素K复合物不同,O抗原的大肠杆菌素蛋白成分可被中和抗体沉淀。大肠杆菌素K与噬菌体T(6)之间不存在可证明的血清学关系。这两种制剂必须被视为独立且不同的实体。