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抗生素领域的白喉(作者译)

[Diphtheria in the area of antibiotics (author's transl)].

作者信息

Meyer zum Gottesberge A, Quante M

出版信息

Laryngol Rhinol Otol (Stuttg). 1976 Sep;55(9):707-10.

PMID:135895
Abstract

In Düsseldorf repeated incidences of severe membranous angina were observed, several cases of which had a fatal outcome. Though the bacteriological proof could only be firnished in one case, in the rest of the cases there was also the strong suspicion of diphtheria. To guarantee the final diagnosis, it is necessary, to make the throat swab before the antibiotic therapy begins since only a single dosis of penicillin jeopardises the demonstration of the infection agent. It must urgently be minded of the necessity, that in cases of suspicion a diphtheria antitoxin should be given in good time, not waiting for the bacteriological clarification, since already a whole generation of physicians from their personal experience is no longer up to date on the clinical picture of diphtheria.

摘要

在杜塞尔多夫观察到多次严重膜性心绞痛的发病情况,其中几例导致了致命后果。尽管仅在一例中完成了细菌学证明,但在其余病例中也强烈怀疑是白喉。为确保最终诊断,有必要在抗生素治疗开始前进行咽拭子检查,因为仅一剂青霉素就会危及感染病原体的检测。必须紧急提醒注意,在疑似病例中应及时给予白喉抗毒素,不要等待细菌学明确诊断,因为整整一代医生根据他们的个人经验,对白喉的临床症状已不再熟悉。

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