Vila J, Esplugues J, Orts A, García-Díez J M, Morcillo E
Rev Esp Fisiol. 1976 Sep;32(3):217-30.
The experimental relation between adrenergic nervous system and ulcus has been studied. Administration of adrenaline to rats did not induce any ulcers, or showed any noteworthy modification in the studied pH, acidity and peptic activity of gastric content parameters. The number of ulcers induced by the Shay method, acidity and peptic activity decreased after beta receptor blockage. Ko-592 did not induce any significant change on these parameters when the animals were subjected to stress conditions by restraint. Beta receptors discretely participate in ulcer pathology.