通过脑内或脑膜内接种急性可移植性白血病L 5222在大鼠中诱导脑膜白血病的发生。
Development of meningeal leukemia in rats by intracerebral or intrameningeal inoculation of the acute transplantable leukemia L 5222.
作者信息
Fiebig H H, Zeller W J, Schmähl D
出版信息
Z Krebsforsch Klin Onkol Cancer Res Clin Oncol. 1976 Aug 30;86(3):287-92. doi: 10.1007/BF00286947.
PMID:136103
Abstract
An experimental model of meningeal leukemia is developed by intracerebral or intrameningeal inoculation of cells from the transplantable acute rat leukemia L 5222. The histopathological pattern is similar to that observed in central nervous system leukemia in man. The leukemia L 5222 becomes systemic 2 days after intracerebral inoculation.
摘要
通过向脑内或脑膜内接种可移植的大鼠急性白血病L 5222的细胞，建立了脑膜白血病的实验模型。其组织病理学模式与人类中枢神经系统白血病中观察到的相似。脑内接种后2天，白血病L 5222发展为全身性疾病。
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