DE ROBERTIS E, LASANSKY A
J Biophys Biochem Cytol. 1958 Nov 25;4(6):743-6. doi: 10.1083/jcb.4.6.743.
The fine structure of the cone cell of the rabbit is described and compared wtih that of the rod. The cone outer segment consists of a pile of flattened sacs with two membranes 30 A thick and a regular clear space in between of about 30 A. The membrane of the rod sacs is slightly thicker ( approximately 40 A) and the clear space is less regular and frequently absent in the deeper regions. The distance between sacs is from 85 to 95 A in the cone and from 110 to 120 A in the rod, and the total repeating period is about 190 A and 210 A, respectively. These results are discussed in relation to the concentration of solids in both photoreceptors. A connecting cilium was observed in the cone cell and compared with that previously described in rods (4). This finding suggests that morphogenetically the cone may also result of the differentiation of a primitive cilium (5). The inner segment of the cone shows a distal portion with large concentration of elongated mitochondria and a proximal one with a large Golgi complex in the axis surrounded by components of the endoplasmic reticulum. It is concluded that both photoreceptors have a similar general plan of submicroscopic organization, with some minor difference in fine structure probably related to their specific chemical composition and function.
本文描述了兔视锥细胞的精细结构，并与视杆细胞的精细结构进行了比较。视锥细胞外段由一堆扁平囊泡组成，囊泡有两层厚约30埃的膜，两层膜之间有一个约30埃的规则透明间隙。视杆细胞囊泡的膜稍厚（约40埃），透明间隙不太规则，在较深区域常常不存在。视锥细胞中囊泡之间的距离为85至95埃，视杆细胞中为110至120埃，总的重复周期分别约为190埃和210埃。结合两种光感受器中固体物质的浓度对这些结果进行了讨论。在视锥细胞中观察到了连接纤毛，并与先前在视杆细胞中描述的连接纤毛进行了比较（4）。这一发现表明，从形态发生学角度来看，视锥细胞也可能源于原始纤毛的分化（5）。视锥细胞的内段显示，远端部分有大量密集的细长线粒体，近端部分在轴线上有一个大的高尔基体复合体，周围是内质网成分。得出的结论是，两种光感受器具有相似的亚微观组织结构总体模式，在精细结构上存在一些细微差异，这可能与它们特定的化学组成和功能有关。
