CRONHEIM G, GOURZIS J T, TOEKES I M
Science. 1958 Dec 19;128(3338):1570-1. doi: 10.1126/science.128.3338.1570.
Trimethoxybenzoyl-glycine-diethylamide induced in dogs and cats normal sleep without preceding ataxia. A five- to ten-fold increase of the soporific dose resulted in restlessness and disorientation instead of sleep. In man, oral doses of 500 to 1500 mg caused sedation or drowsiness, or both, in half the cases. No spindling or drug-induced artifacts were found in electroencephalographic recordings.
三甲氧基苯甲酰甘氨酸二乙酰胺可使犬猫进入正常睡眠，且无共济失调前驱症状。催眠剂量增加五至十倍会导致躁动和定向障碍，而非睡眠。对人而言，口服500至1500毫克剂量时，半数病例会出现镇静或嗜睡，或两者皆有。脑电图记录中未发现纺锤波或药物诱发的伪迹。
