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[聚对二氧环己酮用于踝关节上腓侧韧带慢性功能不全的韧带修复:实验与临床经验]

[Ligament repair with PDS (polydioxanone) in chronic insufficiency of the fibular ligament of the upper ankle joint: experimental and clinical experiences].

作者信息

Bär B W, Tausch W, Buntrock P

机构信息

Klinik für Chirurgie, Humboldt-Universität zu Berlin.

出版信息

Aktuelle Traumatol. 1992 Oct;22(5):229-35.

PMID:1361714
Abstract

From September 1988 till February 1989, 14 patients with chronic ligamentous rupture of the ankle had been operated on using PDS-plasty. Of 12 patients checked in follow-up examination (mean postoperative period 45 weeks), only two showed good or very good results. Most patients had the same signs of chronic instability as preoperatively. Two patients had been reoperated on. Intraoperatively we did not find a biological substitute along the PDS guide line. In an experiment on the rat we examined histological changes and tensile strength at appointed times. Histological data showed no biological substitute of PDS. We also found residues of PDS even after 300 days. After a short time loss of tensile strength occurred. In view of an aseptical necrosis that occurred in our experiments, we must point out the risk of foreign body granulomas.

摘要

1988年9月至1989年2月期间,14例踝关节慢性韧带断裂患者接受了聚对二氧环己酮(PDS)修复术。在接受随访检查的12例患者中(术后平均时间为45周),只有两例显示出良好或非常好的效果。大多数患者仍有与术前相同的慢性不稳定体征。有两例患者接受了再次手术。术中我们未在PDS引导线上发现生物替代物。在一项对大鼠的实验中,我们在指定时间检查了组织学变化和拉伸强度。组织学数据显示PDS没有生物替代物。即使在300天后,我们也发现了PDS的残留物。短时间后拉伸强度就出现了损失。鉴于我们实验中发生的无菌性坏死,我们必须指出异物肉芽肿的风险。

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