Scheuer J, Bhan A K, Penpargkul S, Malhotra A
Adv Cardiol. 1976;18(0):15-25. doi: 10.1159/000399509.
The effects of a moderate physical training program on the hearts of rats have been studied. The mechanical responses of these hearts are improved. Possible contributing factors in this improvement are increased coronary reserve and capacity to deliver oxygen to the myocardium, increased myocardial glycogen stores and increased turnover of fatty acids through the endogenous triglyceride pool. Myocardial oxidative compounds and high energy phosphate stores are not altered. Major changes are found in the energy utilization pathways. Actomyosin, myosin, and heavy meromyosin ATPase activity and binding activity of isolated sarcoplasmic reticulum are all enhanced. Sulfhydryl control of the active site of myosin ATPase is altered. The biochemical effects of conditioning are short lived when training is decreased or discontinued.
已经研究了适度体育训练计划对大鼠心脏的影响。这些心脏的机械反应得到改善。这种改善的可能促成因素包括冠状动脉储备增加、向心肌输送氧气的能力增强、心肌糖原储备增加以及通过内源性甘油三酯池的脂肪酸周转率提高。心肌氧化化合物和高能磷酸储备没有改变。在能量利用途径中发现了主要变化。肌动球蛋白、肌球蛋白和重酶解肌球蛋白ATP酶活性以及分离的肌浆网的结合活性均增强。肌球蛋白ATP酶活性位点的巯基控制发生改变。当训练减少或停止时，适应性调节的生化效应持续时间较短。
