LEWIS W B
Calif Med. 1959 Jan;90(1):26-8.
A new skeletal muscle relaxant, methocarbamol, was used in the treatment of 38 patients with a variety of severe neurological disorders and skeletal muscle spasm states.Eighty-two per cent of the patients studied obtained a beneficial result ranging from excellent to fair. Mild side effects such as drowsiness were observed in five patients, mild weakness in three patients and excessive perspiration in one. In two of the five patients who complained of drowsiness, it disappeared upon reduction of dosage and did not reappear when original dosage was reinstituted.
一种新型骨骼肌松弛剂——美索巴莫,被用于治疗38例患有各种严重神经疾病和骨骼肌痉挛状态的患者。在所研究的患者中,82%取得了从极佳到尚可的有益效果。5例患者出现了如嗜睡等轻度副作用,3例患者出现轻度虚弱,1例患者出现多汗。在抱怨嗜睡的5例患者中,有2例在减少剂量后嗜睡消失,恢复原剂量后未再次出现。