快速更换浴液时的破伤风反应：横向小管的电紧张性去极化可能从日本林蛙骨骼肌的肌浆网释放Ca2+ 。

Tetanus responses under rapid bath solution change: electrotonic depolarization of transverse tubules may release Ca2+ from sarcoplasmic reticulum of Rana japonica skeletal muscle.

Fujishiro N, Kawata H

Department of Physiology, School of Medicine, Fukuoka University, Japan.

Comp Biochem Physiol Comp Physiol. 1992 Dec;103(4):661-6. doi: 10.1016/0300-9629(92)90163-k.

Abstract

Single skeletal muscle fibers were transferred from a normal Ringer solution to Na+ ion free solution, and vice versa, and tetanus responses were recorded immediately after the transfer. 2. Fractional tetanus tension recorded immediately after the displacement from the Na+ ion free solution to normal Ringer solution was dependent on fiber diameter. 3. Diffusion of Na+ ions along the transverse tubules was simulated [apparent diffusion constant was 3.11 x 10(-6) (cm2/s)]. 4. Our results suggest that the electronic spreading of membrane potential, caused by an action potential in the transverse tubules, could release Ca2+ ions from sarcoplasmic reticulum.

摘要

将单个骨骼肌纤维从正常林格液转移至无钠溶液，反之亦然，并在转移后立即记录强直收缩反应。2. 从无钠溶液转移至正常林格液后立即记录的强直收缩张力分数取决于纤维直径。3. 模拟了钠离子沿横管的扩散[表观扩散常数为3.11×10⁻⁶(cm²/s)]。4. 我们的结果表明，由横管中的动作电位引起的膜电位电传播可从肌浆网释放钙离子。