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肝脏中一种抑制骨髓胸腺嘧啶生物合成的物质。

A substance in liver which inhibits thymine biosynthesis by bone marrow.

作者信息

DINNING J S, WILES L

出版信息

Science. 1959 Feb 6;129(3345):336. doi: 10.1126/science.129.3345.336.

DOI:10.1126/science.129.3345.336
PMID:13624729
Abstract

A substance was extracted from rabbit liver which inhibited the incorporation of formate into bone-marrow thymine in vitro. In view of the important role of thymine biosynthesis in cell division, it is suggested that the inhibitor present in liver is a naturally occurring mitosis inhibitor.

摘要

从兔肝脏中提取出一种物质，该物质在体外能抑制甲酸掺入骨髓胸腺嘧啶。鉴于胸腺嘧啶生物合成在细胞分裂中的重要作用，有人提出肝脏中存在的这种抑制剂是一种天然存在的有丝分裂抑制剂。

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