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Demonstration of HTLV-related proviral DNA sequences and antibodies reactive with HTLV internal proteins in an Hungarian patient with Sézary syndrome.

作者信息

Kiss J, Kiss A, Tóth F D, Surányi P, Szegedi A, Rak K

机构信息

Institute of Microbiology, University Medical School, Debrecen, Hungary.

出版信息

Leuk Lymphoma. 1992 Aug;7(5-6):511-5. doi: 10.3109/10428199209049809.

DOI:10.3109/10428199209049809
PMID:1362917
Abstract

DNA sequences distantly related to the proviral DNA of HTLV-I were found in the leukemic cells of a Hungarian patient suffering from Sézary syndrome. Serum samples from the patient contained antibodies reactive with the internal core polypeptides of HTLV-I and HTLV-II, but not with the env gene encoded type-specific HTLV antigens. The husband and daughter of the patient also had antibodies of the same specificity. These findings suggest the presence of a virus distantly related to HTLV-I and HTLV-II.

摘要

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