LINCOLN C S, NORDSTROM R C, BATTS E E
Calif Med. 1959 Feb;90(2):126-7.
A new antipruritic, trimeprazine, was used in the treatment of itching associated with a variety of dermatologic disorders in 215 patients.Good to excellent relief of itching was experienced by 71 per cent of the patients, fair relief by 15 per cent and poor relief by 14 per cent.Side effects included mild and transient drowsiness or dizziness that cleared spontaneously; six cases of drowsiness that necessitated discontinuance of the drug; three cases of drowsiness that was controlled by reduction of the dosage; and one case of generalized eruption that cleared upon discontinuance of the drug.
一种新型止痒药——三甲丙嗪，用于治疗215例与多种皮肤病相关的瘙痒。71%的患者瘙痒得到了良好至极佳的缓解，15%的患者缓解效果尚可，14%的患者缓解效果不佳。副作用包括轻度且短暂的嗜睡或头晕，可自行缓解；6例嗜睡患者需停药；3例嗜睡患者通过减少剂量得到控制；1例全身性皮疹患者停药后皮疹消退。
