单个脊髓运动神经元的细胞外电位。
Extracellular potentials from single spinal motoneurons.
作者信息
FREYGANG W H, FRANK K
出版信息
J Gen Physiol. 1959 Mar 20;42(4):749-60. doi: 10.1085/jgp.42.4.749.
Abstract
Extracellular action potentials found close to the surface of motoneurons are related to the intracellular spikes. Evidence is cited to support the assumption that the extracellular spikes have the same time course as the membrane current at the site of recording. Simultaneously recorded intracellular and extracellular spikes are compared. Intracellular spikes are transformed, by means of a circuit which is equivalent to the extracellular recording situation, into transients that are like those appearing extracellularly. Evidence is given that the recordings are from the cell bodies of motoneurons. The results show that the membrane at the extracellular recording site does not produce a spike since the time course of the extracellular potentials is determined by the passive properties of the membrane.
摘要
在运动神经元表面附近发现的细胞外动作电位与细胞内尖峰相关。文中引用了证据来支持细胞外尖峰与记录部位膜电流具有相同时间进程这一假设。对同时记录的细胞内和细胞外尖峰进行了比较。通过一个等同于细胞外记录情况的电路，将细胞内尖峰转换为类似于细胞外出现的瞬变信号。文中给出了记录来自运动神经元细胞体的证据。结果表明，细胞外记录部位的膜不会产生尖峰，因为细胞外电位的时间进程由膜的被动特性决定。
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