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Studies of nonsedative antihistamines. II. Assessment of its antihistaminic potency.

作者信息

Aparicio S, Granel C, Randazzo L, Valencia M, Olivé Pérez A

机构信息

Hospital de la Santa Creu i Sant Pau, Unitat d'Al.lèrgia, Barcelona.

出版信息

Allergol Immunopathol (Madr). 1992 Sep-Oct;20(5):207-10.

PMID:1363340
Abstract

An analysis is made of the effectiveness of terfenadine at dosages of 60 and 120 mg, of cetirizine at a dose of 10 mg, and of loratadine and ebastine at a dose of 10 mg in inhibiting the papule induced by 20 mcg of intradermal histamine. Although all produced significant inhibition, cetirizine and terfenadine 120 mg showed a significantly greater inhibition coefficient than loratadine.

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