[七鳃鳗（Lampetra fluviatilis）中离心视觉神经元介质的免疫细胞化学研究]
[Immunocytochemical research on mediators of centrifugal visual neurons in lampreys (Lampetra fluviatilis)].
作者信息
Rio J P, Dalil N, Kirpitchnikova E, Vesselkin N P, Versaux-Botteri C, Reperant J
机构信息
Laboratoire de Neuromorphologie, Développement, Evolution, I.N.S.E.R.M. U 106, Hôpital de la Salpêtrière, Paris.
出版信息
C R Acad Sci III. 1992;315(12):505-11.
The aim of this study has been to investigate different neuroactive substances in the lamprey centrifugal visual neurons (CVN) by combining axonal tracing methods and immunocytochemistry. The CVN somata are immunonegative to antibodies recognizing FMRF-amide, LH-RH, 5 HT and TH, but immunopositive to an anti-GABA antiserum (GABA+) in a proportion of 40%. In the retina, the GABA+ axon terminals mainly synapse upon GABA+ and GABA- amacrine cell bodies and dendrites, and on dendrites of GABA- ganglion cells.
本研究的目的是通过结合轴突追踪方法和免疫细胞化学来研究七鳃鳗离心视觉神经元（CVN）中的不同神经活性物质。CVN 胞体对识别 FMRF 酰胺、促黄体生成素释放激素、5-羟色胺和酪氨酸羟化酶的抗体呈免疫阴性，但对一种抗 GABA 抗血清（GABA+）呈免疫阳性，比例为 40%。在视网膜中，GABA+轴突终末主要与 GABA+和 GABA-无长突细胞的胞体和树突以及 GABA-神经节细胞的树突形成突触。
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