COBB N L, SCOVILLE W B
Calif Med. 1959 Apr;90(4):261-3.
In a series of 19 patients who had hypophysectomy for palliation of cancer of the breast, all had striking relief of pain. Objective evidence of remission of disease was observed in ten patients. The survival time after operation averaged 19.8 months for patients who had remission and 2.1 months for patients who did not. Results were better in patients who had had cancer for a long time before operation than in those who had had the disease a relatively short time. Also it was noted that results were better in patients who had had preoperative response to endocrine therapy than in those who had not. Hence these factors may be considered in selection of patients for hypophysectomy.
在一组因缓解乳腺癌症状而接受垂体切除术的19例患者中，所有患者的疼痛均得到显著缓解。10例患者观察到疾病缓解的客观证据。缓解患者术后平均生存时间为19.8个月，未缓解患者为2.1个月。术前患癌时间长的患者比患癌时间相对短的患者效果更好。还注意到，术前对内分泌治疗有反应的患者比无反应的患者效果更好。因此，在选择垂体切除术患者时可考虑这些因素。
