[β受体阻滞剂预防食管静脉曲张破裂：一项荟萃分析]
[Beta-blockers in the prevention of the rupture of esophageal varices. A meta-analysis].
作者信息
Dumitraşcu D L
机构信息
Clinica Medicală III, Ciuj.
出版信息
Med Interna. 1992;44(2-4):28-33.
PMID:1364274
Abstract
The meta-analysis of 5 trials for primary prevention and of 18 trials of secondary prevention emphasizes the effect of beta-blockers in the decrease of variceal bleedings in cirrhosis. Beta-blockers are reducing the bleeding events with 32% in the primary prevention and with 28% in the secondary prevention. The mortality is reduced by 15%, respectively by 23%. This is the first meta-analysis reported in the Romanian gastroenterological literature.
摘要
对5项一级预防试验和18项二级预防试验的荟萃分析强调了β受体阻滞剂在降低肝硬化静脉曲张出血方面的作用。β受体阻滞剂在一级预防中使出血事件减少32%，在二级预防中减少28%。死亡率分别降低了15%和23%。这是罗马尼亚胃肠病学文献中报道的第一项荟萃分析。
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