Kuneva T, Ivanova S
Probl Khig. 1992;17:213-8.
Clinical studies are performed on 15 workers from the chemical and pharmaceutic plant "Stanke Dimitrov". Seven of the workers are with acute poisoning from aniline and phenylhydrazine, and eight are exposed to a chronic combined effect of a large group of organic solvents. The clinic and laboratory examinations aim at clarifying the liver and kidney functions, the state of the blood and nervous systems. The tests embrace also blood test morphology and osmotic resistance of erythrocytes, iron, correlation of haemoglobin types, electrolytes, transaminase, GGTP, lipid metabolism, iron-binding capacity. Moderately increased transaminase activity is found in 2/3 of the examined. In four of the workers is registered expressed anaemic and lung syndrome. The following diagnoses are accepted: chronic combined effect of organic solvents--in 3 workers; chronic poisoning with aniline and other solvents--in 1; toxic hepatitis--in 4, with no data for poisoning--in 7. The leading clinical syndromes in acute and chronic combined effect of organic solvents are discussed.
对来自“斯坦克·季米特洛夫”化工制药厂的15名工人进行了临床研究。其中7名工人因苯胺和苯肼急性中毒，8名工人暴露于一大类有机溶剂的慢性联合作用之下。临床和实验室检查旨在明确肝脏和肾脏功能、血液和神经系统状况。检测还包括血液形态学、红细胞渗透抵抗力、铁、血红蛋白类型相关性、电解质、转氨酶、γ-谷氨酰转肽酶、脂质代谢、铁结合能力。在三分之二的受检者中发现转氨酶活性中度升高。4名工人出现明显的贫血和肺部综合征。做出了以下诊断：有机溶剂慢性联合作用——3名工人；苯胺和其他溶剂慢性中毒——1名工人；中毒性肝炎——4名工人；无中毒数据——7名工人。讨论了有机溶剂急性和慢性联合作用中的主要临床综合征。
