Rehák J
Department of Ophthalmology, Medical Faculty, Palacký University, Olomouc, Czechoslovakia.
Acta Univ Palacki Olomuc Fac Med. 1992;134:101-3.
Rubeosis iridis is one of the severest complications of the occlusive diseases of retinal vessels associated with retinal hypoxia. In the pathogenesis of rubeosis, the author emphasizes the chronicity of retinal hypoxia which leads to the production of the vasoproliferative substance. This so-called vasoproliferative factor then induces the new formation of vessels on the retina, the optic disc, the iris and the anterior chamber angle. Neovascularization of the anterior chamber angle then very often results in the development of the prognostically very unfavourable neovascular glaucoma. It shows that the most effective methods of treatment of rubeosis iridis are the so-called coagulation techniques-panretinal photocoagulation or cryocoagulation. By application of these techniques, we achieve the destruction of the anatomical substrate which is responsible for the production of the vasoproliferative substance, and the result is involution of rubeosis on the iris and in the anterior chamber angle.
虹膜红变是与视网膜缺氧相关的视网膜血管闭塞性疾病最严重的并发症之一。在虹膜红变的发病机制中，作者强调视网膜缺氧的慢性化会导致血管增生物质的产生。这种所谓的血管增生因子随后会诱导视网膜、视盘、虹膜和前房角出现新的血管形成。前房角的新生血管化常常会导致预后非常不利的新生血管性青光眼的发生。这表明治疗虹膜红变最有效的方法是所谓的凝固技术——全视网膜光凝或冷冻凝固。通过应用这些技术，我们能够破坏负责产生血管增生物质的解剖学基础，结果是虹膜和前房角的虹膜红变消退。
