Lichnovský V, Lojda Z, Bocek M
Institut für Histologie und Embryologie Medizinische Fakultät der Polacký Universität, Olomouc, Tschechoslowakei.
Acta Univ Palacki Olomuc Fac Med. 1992;134:33-7.
The histochemical distribution of gamma-glutamyltranspeptidase (GGT) in organs of human embryos and fetuses was studied. In youngest embryos (4-7 weeks), a high GGT activity in the epithelium of the proximal part of embryonic intestine was recorded. Maximum of the activity was localised on membranes of luminal surface of primitive epithelium. High GGT activity in differentiating hepatocytes was also observed. In older fetuses (8-20 weeks) the activity of GGT gradually increases. In the epithelium of intestinal villi apex-basis gradient of the activity was recorded. The highest GGT activity in differentiating brusch border of the epithelium of proximale tubuli of fetal kidney was observed as well.
研究了γ-谷氨酰转肽酶（GGT）在人类胚胎和胎儿器官中的组织化学分布。在最年幼的胚胎（4 - 7周）中，记录到胚胎肠道近端上皮中GGT活性较高。活性最大值位于原始上皮腔表面的膜上。在分化的肝细胞中也观察到较高的GGT活性。在较大的胎儿（8 - 20周）中，GGT活性逐渐增加。在肠绒毛上皮中记录到活性从顶端到底部的梯度变化。在胎儿肾脏近端小管上皮分化的刷状缘中也观察到最高的GGT活性。
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