吗啡对多形核白细胞和单核细胞吞噬活性的影响。
Effect of morphine on phagocytic activity of the polymorphonuclears and monocytes.
作者信息
Luza J
机构信息
Department of Physiology, Palacký University, Olomouc, Czechoslovakia.
出版信息
Acta Univ Palacki Olomuc Fac Med. 1992;134:47-50.
The effect of morphine on the phagocytic activity of the polymorphonuclears (PMN), and monocytes in peripheral blood of laboratory rats of inbred Wistar strain was studied in vitro. Phagocytic activity of both types of the white blood cells was examined by the classical method using microspherical hydrophilic particles (Hema-particles), phagocytosis of the Hema-particles was determined by light microscopy. For evaluation of the leukocyte adherence, the method of MacGregor was used. Morphine was proved to influence phagocytic activity of individual types of the leukocytes in different way. Phagocytic activity of the PMNs was suppressed (by 14.0%), and that of monocytes was potentiated (by 17.1%).
在体外研究了吗啡对近交系Wistar大鼠外周血中多形核白细胞（PMN）和单核细胞吞噬活性的影响。使用微球形亲水性颗粒（血细胞颗粒）通过经典方法检测这两种类型白细胞的吞噬活性，通过光学显微镜确定血细胞颗粒的吞噬作用。为评估白细胞黏附，采用了MacGregor方法。结果证明，吗啡以不同方式影响各类型白细胞的吞噬活性。多形核白细胞的吞噬活性受到抑制（降低了14.0%），而单核细胞的吞噬活性则增强（提高了17.1%）。
Zotero 插件