Deininger P L, Batzer M A, Hutchison C A, Edgell M H
Department of Biochemistry and Molecular Biology, Louisiana State University Medical Center, New Orleans 70112.
Trends Genet. 1992 Sep;8(9):307-11. doi: 10.1016/0168-9525(92)90262-3.
The analysis of species-specific subfamilies of both the LINE and SINE mammalian repetitive DNA families suggests that such subfamilies have arisen by amplification of an extremely small group of 'master' genes. In contrast to the master genes, the vast majority of both SINEs and LINEs appear to behave like psudogenes in their inability to undergo extensive amplification.
对哺乳动物长散在核元件(LINE)和短散在核元件(SINE)这两个重复DNA家族的物种特异性亚家族分析表明,这些亚家族是由一小群“主”基因的扩增产生的。与主基因不同,绝大多数SINE和LINE似乎表现得像假基因,无法进行广泛扩增。