Nutr Rev. 1990 Jun;48(6):255-8. doi: 10.1111/j.1753-4887.1990.tb02951.x.
Pyridoxal kinase, a key enzyme in the formation of vitamin B6 coenzymes, requires a zinc-ATP complex as a substrate. Recent findings show that zinc-metallothionein facilitates the formation of the zinc-ATP complex. Thus, the concentration of zinc-metallothionein in tissues may serve in the regulation of vitamin B6 metabolism.
吡哆醛激酶是维生素B6辅酶形成过程中的关键酶,它需要锌 - ATP复合物作为底物。最近的研究结果表明,锌 - 金属硫蛋白有助于锌 - ATP复合物的形成。因此,组织中锌 - 金属硫蛋白的浓度可能参与维生素B6代谢的调节。