鉴定吲哚丙酮酸为瑞贝克霉素生物合成的中间体。
Identification of indolepyruvic acid as an intermediate of rebeccamycin biosynthesis.
作者信息
Lam K S, Forenza S, Doyle T W, Pearce C J
机构信息
Bristol-Myers Squibb Company, Wallingford, CT 06492.
出版信息
J Ind Microbiol. 1990 Dec;6(4):291-4. doi: 10.1007/BF01575876.
PMID:1366997
Abstract
Experimental evidence is presented to demonstrate that indolepyruvic acid is an intermediate in the rebeccamycin biosynthetic pathway. [3-14C]Indolepyruvic acid was prepared and efficiently incorporated (8%) into rebeccamycin by Saccharothrix aerocolonigenes.
摘要
实验证据表明吲哚丙酮酸是瑞贝卡霉素生物合成途径中的一个中间体。制备了[3-¹⁴C]吲哚丙酮酸，并被栖动物糖丝菌高效掺入（8%）到瑞贝卡霉素中。
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