Brookes A J, Porteous D J
MRC Human Genetics Unit, Western General Hospital, Edinburgh, UK.
Trends Biotechnol. 1992 Jan-Feb;10(1-2):40-4. doi: 10.1016/0167-7799(92)90166-s.
Many analytical molecular genetic techniques developed over the past decade have evolved primarily to tackle the problem of targeting or isolating sequences of interest in complex mixtures. A new approach to this problem, Coincident Sequence Cloning (CSC), involves integrating a pair of DNA mixtures in such a way as to isolate any shared sequence components.
在过去十年间开发的许多分析性分子遗传学技术，主要是为了解决在复杂混合物中靶向或分离感兴趣序列的问题而发展起来的。解决这个问题的一种新方法——重合序列克隆（CSC），涉及以某种方式整合一对DNA混合物，以分离出任何共享的序列成分。
