Trevenzoli M, Cattelan A M, Marino F, Marchioro U, Cadrobbi P
Division of Infectious Diseases, General Hospital and University of Padua, Italy.
Postgrad Med J. 2003 Sep;79(935):535-8. doi: 10.1136/pmj.79.935.535.
Sarcoidosis occurring in patients with AIDS is rare. This infrequent association has been attributed to the impairment of the immune system that may interfere with the granuloma formation in HIV infected patients. However, the introduction of highly active antiretroviral therapy (HAART) has brought about a substantial and sustained increase in CD4+ T lymphocyte cells, and has consequently led to the development of the so called "immune restoration disease". The case of an HIV infected man who developed sarcoidosis after the initiation of HAART is described. Skin nodule images and histological specimens are reported. The association between sarcoidosis and HIV infection is also reviewed.
艾滋病患者中发生结节病的情况较为罕见。这种不常见的关联归因于免疫系统受损，这可能会干扰HIV感染患者的肉芽肿形成。然而，高效抗逆转录病毒疗法（HAART）的引入使CD4 + T淋巴细胞显著且持续增加，从而导致了所谓的“免疫重建疾病”的发生。本文描述了一名HIV感染男性在开始HAART后发生结节病的病例。报告了皮肤结节图像和组织学标本。还对结节病与HIV感染之间的关联进行了综述。
