Raju G K, Cooney C L
Biotechnology Process Engineering Center, Massachusetts Institute of Technology.
Curr Opin Biotechnol. 1992 Feb;3(1):40-4. doi: 10.1016/0958-1669(92)90123-z.
Fermentation monitoring continues to be the focus of much research. Over the last year, important strides were made in improving bioprocess monitoring using NADH fluorescence, viscosity, affinity techniques, enzyme and microbial sensors, calorimetry, flow injection analysis and bioluminescence. Better fermentation monitoring is important for improving understanding, operation, development and control of the process. We expect progress in these areas of research to continue. In addition, we highlight some non-conventional approaches.
发酵监测仍是众多研究的焦点。在过去一年里，利用烟酰胺腺嘌呤二核苷酸（NADH）荧光、粘度、亲和技术、酶和微生物传感器、量热法、流动注射分析以及生物发光等方法在改进生物过程监测方面取得了重要进展。更好的发酵监测对于增进对该过程的理解、操作、开发和控制至关重要。我们预计这些研究领域将继续取得进展。此外，我们还重点介绍了一些非常规方法。
