Dörffel W V, Sugano Y T, Stalling D, Coconu L, Hentschel D, Linss G, Witt Ch
Krankenhaus Hennigsdorf, Innere Klinik, Schwerpunkt Kardiologie, Angiologie und Pneumologie, Akademisches Lehrkrankenhaus der Freien Universität Berlin, Germany.
Pneumologie. 2003 Sep;57(9):503-9. doi: 10.1055/s-2003-42220.
Bronchoscopy is the technique of choice for the evaluation of a stenosis in the large airways. However, no system has been successfully employed for the bronchoscopic measurement of airway stenosis. The purpose of these study was the development and validation of a method for measuring the cross-sectional areas in the large airways. Furthermore, this application should be used for the 3D-reconstruction and visualisation of airway stenosis. A laser probe inserted into the operating channel of the bronchoscope enabled assessment of the distance between the images and the tip of the bronchoscope by means of projecting a ring of light on to the endoluminal wall. Image distortion due to the wide-angle lens was corrected by a computer program developed by us. Plastic tubes with known diameters were used for validation. Additionally, distortion-corrected bronchoscopic images were compared with distortion-free videoscopic image analysis of tracheal slices taken from pigs. When plastic tubes were used, the correlation coefficient (r) was slightly higher (r = 0,99, p < 0,01) than the correlation of cross-sectional areas between bronchoscopic and videoscopic images of tracheal slices (r = 0,88, p < 0,01). Furthermore the system could be used in a few patients for 2D and 3D measurement and visualisation of airway stenosis. Application of the present method offer quantitative assessment of airway stenosis located in the large airways.
支气管镜检查是评估大气道狭窄的首选技术。然而，尚无系统成功用于支气管镜下气道狭窄的测量。本研究的目的是开发并验证一种测量大气道横截面积的方法。此外，该应用应可用于气道狭窄的三维重建和可视化。将激光探头插入支气管镜的操作通道，通过向腔内壁投射一圈光来评估图像与支气管镜尖端之间的距离。我们开发的计算机程序校正了广角镜头导致的图像失真。使用已知直径的塑料管进行验证。此外，将失真校正后的支气管镜图像与取自猪的气管切片的无失真视频镜图像分析进行比较。使用塑料管时，相关系数（r）略高于气管切片支气管镜图像与视频镜图像之间横截面积的相关性（r = 0.99，p < 0.01；r = 0.88，p < 0.01）。此外，该系统可用于少数患者气道狭窄的二维和三维测量及可视化。本方法的应用可对大气道中的气道狭窄进行定量评估。
