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一名25日龄婴儿因胃畸胎瘤合并局灶性神经母细胞瘤导致严重贫血。

Severe anemia in a 25-day-old infant due to gastric teratoma with focal neuroblastoma.

作者信息

Hook Samantha, Spicer Richard, Williams Jonathan, Grier David, Lowis Steve, Foot Annabel, Sergi Consolato

机构信息

Department of Paediatric Surgery, Children's Hospital, Bristol, United Kingdom.

出版信息

Am J Perinatol. 2003 Jul;20(5):233-7. doi: 10.1055/s-2003-42343.

Abstract

Gastric teratoma is an extremely rare embryonic neoplasm containing tissue from all three germ layers (ectoderm, endoderm, and mesoderm). A 25-day-old infant presented with anemia and a palpable abdominal mass. Computed tomography (CT) scanning showed a solid and cystic multiloculated tumor of mixed echogenicity and calcifications. An encapsulated bleeding tumor localized to the posterior wall of the stomach with extension to a bowel segment was promptly excised. Histology revealed a grade III immature teratoma with small foci of neuroblastoma. To the best of our knowledge, this is the first infant with gastric teratoma containing foci of neuroblastoma causing bleeding and anemia as presentation symptoms at neonatal age.

摘要

胃畸胎瘤是一种极其罕见的胚胎性肿瘤,包含来自所有三个胚层(外胚层、内胚层和中胚层)的组织。一名25天大的婴儿出现贫血且腹部可触及肿块。计算机断层扫描(CT)显示为一个实性和囊性的多房性肿瘤,具有混合回声和钙化。一个局限于胃后壁并延伸至一段肠管的包膜下出血性肿瘤被迅速切除。组织学检查显示为III级未成熟畸胎瘤,伴有神经母细胞瘤小灶。据我们所知,这是首例患有胃畸胎瘤且伴有神经母细胞瘤灶的婴儿,在新生儿期以出血和贫血作为表现症状。

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