Sakakima Harutoshi, Yoshida Yoshihiro
School of Health Sciences, Faculty of Medicine, Kagoshima University, Sakuragaoka, Kagoshima, Japan.
Arch Phys Med Rehabil. 2003 Sep;84(9):1339-42. doi: 10.1016/s0003-9993(03)00143-6.
To investigate the effect of short duration static stretching of denervated and reinnervated muscle using a histochemical study on the soleus muscle of the rat.
Prospective randomized trial.
University medical school in Japan.
Fifty-four 8-week-old female Wistar rats with a mean weight +/- standard deviation of 185.8+/-9.9g.
After a cold injury was applied to the rat right sciatic nerve, the bilateral soleus muscles were maximally stretched in the dorsiflex posture of the ankle joints for 40 minutes a day, 6 times a week (group S). Rats were compared with nonstretched rats (group D) for up to 4 weeks. Main outcome measures Muscle fiber cross-sectional areas, muscle fiber types, and sciatic nerve morphology.
No apparent difference in the morphologic changes of the sciatic nerve was found between groups D and S. The mean fiber size progressively declined to a minimum 2 weeks after the injury and reversed in the following weeks. At weeks 1 and 2, the mean type I fiber size in group S was significantly larger than in group D (P<.05). The number ratio of the type II to total fibers increased until 3 weeks in group D, whereas the ratio in group S was increased at 2 weeks, and successively decreased.
The mechanical stimuli of static stretching could prevent atrophy of the type I fibers in the denervated muscle and affect the reinnervated muscle fiber-type composition.
通过对大鼠比目鱼肌进行组织化学研究，探讨短期静态拉伸对失神经支配和重新神经支配肌肉的影响。
前瞻性随机试验。
日本大学医学院。
54只8周龄雌性Wistar大鼠，平均体重±标准差为185.8±9.9g。
对大鼠右侧坐骨神经施加冷损伤后，双侧比目鱼肌在踝关节背屈姿势下进行最大程度拉伸，每天40分钟，每周6次（S组）。将大鼠与未拉伸的大鼠（D组）进行长达4周的比较。主要观察指标：肌纤维横截面积、肌纤维类型和坐骨神经形态。
D组和S组坐骨神经的形态学变化无明显差异。损伤后2周，平均纤维大小逐渐下降至最小值，随后几周逆转。在第1周和第2周，S组I型肌纤维的平均大小显著大于D组（P<0.05）。D组II型纤维与总纤维的数量比在3周前增加，而S组的该比例在2周时增加，随后下降。
静态拉伸的机械刺激可防止失神经支配肌肉中I型纤维萎缩，并影响重新神经支配肌肉的纤维类型组成。
