Kaslow D C, Bathurst I C, Barr P J
Molecular Vaccine Section, National Institutes of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD.
Trends Biotechnol. 1992 Nov;10(11):388-91. doi: 10.1016/0167-7799(92)90280-9.
Antibodies to surface proteins of the sexual stages of Plasmodium falciparum block completely the transmission of these malaria parasites. Transmission-blocking vaccines therefore represent a powerful and novel approach to controlling the spread of this lethal disease.
针对恶性疟原虫有性阶段表面蛋白的抗体可完全阻断这些疟原虫的传播。因此,传播阻断疫苗是控制这种致命疾病传播的一种强有力的新方法。