Abdel Hafez A A, Awad I M, Abdel Monem M I
Chemistry Department, Faculty of Science, Assiut University, Egypt.
J Chem Technol Biotechnol. 1992;55(4):333-8. doi: 10.1002/jctb.280550405.
4-Hydroxyacetophenone (1) was reacted with cinnamonitrile derivatives (2-6) to give 3-cyano-4-(substituted phenyl)-6-(p-hydroxyphenyl)-pyridines (7-11). Interaction of compounds 7-9 with 4'-substituted heterocyclo-benzenesulphonyl diazonium chloride gave the corresponding 3-cyano-4-(substituted phenyl)-6-(3'-azobenzene sulphonamido-4'-hydroxyphenyl) pyridines (12-29). The corresponding iron (III) copper (II) and mercury (II) chelates were also prepared in a 1:2 metal-to-ligand ratio. All the synthesized compounds were characterized on the basis of microanalysis, IR and 1H-NMR spectrometry.
4-羟基苯乙酮（1）与肉桂腈衍生物（2 - 6）反应，生成3-氰基-4-（取代苯基）-6-（对羟基苯基）吡啶（7 - 11）。化合物7 - 9与4'-取代杂环苯磺酰重氮氯化物相互作用，得到相应的3-氰基-4-（取代苯基）-6-（3'-偶氮苯磺酰胺基-4'-羟基苯基）吡啶（12 - 29）。还以1:2的金属与配体比例制备了相应的铁（III）、铜（II）和汞（II）螯合物。所有合成化合物均通过微量分析、红外光谱和1H - NMR光谱进行表征。
