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Genetic engineering of beta-lactam antibiotic biosynthetic pathways in filamentous fungi.

作者信息

Skatrud P L

机构信息

Lilly Research Labs., Lilly Corporate Center, Indianapolis, IN 46285.

出版信息

Trends Biotechnol. 1992 Sep;10(9):324-9. doi: 10.1016/0167-7799(92)90258-w.

DOI:10.1016/0167-7799(92)90258-w
PMID:1369089
Abstract

Recombinant DNA technology has facilitated a rapid increase in our knowledge of beta-lactam antibiotic biosynthesis. Using the tools of this technology, beta-lactam biosynthetic genes and proteins have been characterized at the molecular level, cephalosporin-C production has been improved, new beta-lactams produced, and novel beta-lactam biosynthetic pathways have been constructed.

摘要

相似文献

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