Voĭtenko N N, Kolpakov V G
Zh Vyssh Nerv Deiat Im I P Pavlova. 1991 Nov-Dec;41(6):1239-44.
MAO B/MAO A rations and the influence of delta-sleep inducing peptide (DSIP) on the two forms of MAO and on the predisposition to different types of catatonic reactions were compared in rats of GC strain selected from Wistar for predisposition to catalepsy, and in wild rats. In GC rats, the MAO B/MAO A ratio was increased, as compared to Wistar, in the brain stem and hemispheres, whereas in wild rats predisposed to catatonia it was increased, as compared to normal wild rats, only in the hemispheres. In GC rats, this increase of the MAO B/MAO A ratio was due to a decrease of MAO A and increase of MAO B activity, while in wild catatonic rats only due to heightened MAO B activity. Administration of DSIP abolished the susceptibility to catatonic reactions and normalized the MAO B/MAO A ratio both in GC and in wild catatonic rats. There seems to be a partial similarity of physiological mechanisms of catatonic reactions in laboratory albino and in wild rats.
在从Wistar大鼠中挑选出的对僵住症有易感性的GC品系大鼠和野生大鼠中，比较了单胺氧化酶B（MAO B）/单胺氧化酶A（MAO A）的比率，以及δ-睡眠诱导肽（DSIP）对MAO的两种形式和对不同类型紧张性反应易感性的影响。与Wistar大鼠相比，GC大鼠脑干和大脑半球中的MAO B/MAO A比率升高；而与正常野生大鼠相比，易患紧张症的野生大鼠仅在大脑半球中该比率升高。在GC大鼠中，MAO B/MAO A比率的升高是由于MAO A活性降低和MAO B活性增加，而在野生紧张症大鼠中仅由于MAO B活性升高。给予DSIP消除了GC大鼠和野生紧张症大鼠对紧张性反应的易感性，并使MAO B/MAO A比率恢复正常。实验室白化大鼠和野生大鼠的紧张性反应生理机制似乎存在部分相似性。
