[衰老野生挪威大鼠的脑单胺氧化酶，因其对人类缺乏攻击性行为而被选用]
[Brain monoamine oxidase in aging wild Norway rats, chosen for lack of aggressive behavior toward humans].
作者信息
Voĭtenko N N
出版信息
Vopr Med Khim. 1993 Mar-Apr;39(2):28-30.
Monoamine oxidase A and B (MAO A; MAO B) activity was studied in the brain stem and hemispheres of young (4 months) and old (7 months) wild Norway rats of S35-S36 bred for absence of aggressive reactions to men (tame), bred for pronounced aggressive reaction for the same number of generations (aggressive), and those not undergoing any breeding (wild). In young tame rats MAO B activity was lower than in wild ones of the same age. As the animals grew older, in 7 months, MAO B activity increased in the brain stem and hemispheres of all the rats, irrespectively of the type of behavior. Difference in MAO B activity found between tame and wild 4-month rats disappeared at the age of 7 months. MAO A activity did not change either with ageing or due to breeding for behavior.
研究了S35 - S36品系年轻（4个月）和年老（7个月）野生挪威大鼠脑干和大脑半球中A、B型单胺氧化酶（MAO A；MAO B）的活性。这些大鼠分别为因对人无攻击反应（温顺型）而培育、因相同代数具有明显攻击反应（攻击型）而培育以及未经过任何培育（野生型）的。在年轻的温顺型大鼠中，MAO B活性低于同年龄的野生型大鼠。随着动物年龄增长，到7个月时，所有大鼠脑干和大脑半球中的MAO B活性均增加，与行为类型无关。4个月大的温顺型和野生型大鼠之间MAO B活性的差异在7个月大时消失。MAO A活性既不随年龄变化，也不因行为培育而改变。
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