[Mineralization phenomena in the area of long bone fracture wound healing].

Mineralization changes in the area of fracture healing in experimental rabbits were monitored during 28 days of observation. The changes were evaluated with the aid of microscopy in the polarized light, scanning microscopy, infrared spectroscopy and roentgenographic microanalysis in 7, 14, 21, and 28th day of healing process. Mineralization was found to be parallel to the increase of collagen quantity. In the course of healing an arrangement of atom structure of the phoshate takes place. Increasing mineralization is indicated not only by growing values of Ca and P in newly formed bone but also by Ca/P ratio approaching normal values in the final stage of healing. Despite of clinical and radiological features of bony union the process of mineralization is not yet completed. By the 28th day of healing the mineral structure of bone is still remarkably porous resembling cancellous bone. Cortical bone formation occurs on the basis of cancellous bone by organization of the osseous trabeculae.