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[脊柱组织细胞增多症X的长期治疗结果]

[Long-term results of treating histiocytosis X of the spine].

作者信息

Kiepurska A

机构信息

Kliniki Ortopedii CMKP w Otwocku.

出版信息

Chir Narzadow Ruchu Ortop Pol. 1991;56(1-3):17-21.

PMID:1369875
Abstract

A series of 38 children and juveniles with eosinophilic granuloma located in 44 vertebral bodies was treated. The diagnosis was based on typical radiographic appearance, bone marrow examination and histology in cases where the lesion was surgically resected. Management consisted mainly of immobilization and unloading of the spine for 2-3 years. Since 1972 in order to shorten this period posterior arthrodesis of 3 vertebral bodies in thoracic spine and 2 vertebral bodies in lumbar spine by Albee-Gruca method is performed. Radiotherapy was applied in 1 case. In most of the cases full or partial regeneration of the vertebral body was achieved; the height was restored in 76% on average. The extent of regeneration was higher in younger children and in lumbar and cervical spine possibly because of lordosis in these segments.

摘要

对38例患有嗜酸性肉芽肿且病变位于44个椎体的儿童和青少年进行了治疗。诊断依据典型的影像学表现、骨髓检查以及病变手术切除病例的组织学检查。治疗主要包括脊柱固定和减负2至3年。自1972年起,为缩短该时间,采用阿尔比-格鲁卡法对胸椎的3个椎体和腰椎的2个椎体进行后路融合术。1例接受了放疗。大多数病例实现了椎体的完全或部分再生;椎体高度平均恢复了76%。年幼患儿以及腰椎和颈椎的再生程度可能更高,这可能是因为这些节段存在脊柱前凸。

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